What is industrial and systems engineering? The core intellectual theme is the analysis and design of systems involving the interaction between human, machines, or nature. Such systems are highly complex and require modeling of the variability introduced by the human element. These models are incorporated into the overall system design for optimized and robust operations. ISE is interdisciplinary: it encompasses engineering, management, human factor. ISE is systems oriented: it analyzes the interaction and interplay between components in complex networks. ISE is a unique engineering discipline: it integrates the quantitative engineering approach with qualitative insights of human behavior. Learn more.